 Precision viticulture is experiencing rapid growth due to the availability of cost-effective instruments and methods for data collection and analysis, such as unmanned aerial vehicles, UAVs. These instruments are able to compete with traditional platforms like satellites and aircraft because they offer low operational costs, high operational flexibility, and high spatial resolution of imagery. To optimize the use of these technologies for precision viticulture, their technical, scientific, and economic performances must be assessed. This study compared NDVI surveys conducted using UAV, aircraft, and satellite to determine which platform best represents the intravenured vegetation spatial variability. Additionally, the advantages and disadvantages of each technology were evaluated through a cost analysis based on the size of the area being surveyed. Results show that all platforms provide similar results when applied to vineyards with coarse vegetation gradients and large vegetation clusters. However, in more heterogeneous vineyards, low-resolution images fail to capture some of the intravenured variability. Furthermore, the cost analysis revealed that UAV is most beneficial for smaller areas and that a break-even point. This article was authored by Alessandro Matisse, Piero Toscano, Salvatore Filippo, Di Gennaro, and others.