 Magnesium-based hydride alloys have the potential to be used as a viable alternative to traditional hydrogen storage materials due to their high hydrogen storage capacity, abundance, and low cost. However, slow kinetics and stable thermodynamics limit their practical applications. In contrast to the significant progress made in enhancing the hydrogenation slash dehydrogenation kinetics, thermodynamic tuning remains a major challenge for MG-based alloys. Current strategies for achieving thermodynamic tuning include alloying, nanostructuring, and changing the reaction pathway. While these methods have resulted in some success, they are not yet sufficient for practical application. This review paper discusses the advantages and drawbacks of each approach and suggests that finding reversible systems with high hydrogen capacity and effectively tailored reaction enthalpies could lead to more effective thermodynamic tuning of MG-based hydrogen storage alloys. This article was authored by Min Zhu, Yan Shan Lu, Lu Zheng Ouyang, and others. We are article.tv, links in the description below.