 The ascorbate glutathione, as a GSH, pathway plays a key role in protecting plants against oxidative stress. It consists of several enzymes which are involved in the detoxification of reactive oxygen species, ROS. Overexpression of these enzymes can increase the level of ascorbate and glutathione, thus providing protection against oxidative damage. Additionally, the as a GSH pathway has been shown to interact with other defense systems in plants, such as the H2O2 scavenging system, resulting in improved tolerance to abiotic stress. This article was authored by Mirza Hassanizaman, M. H. M. Boranedin Booyan, Tofika Islamani, and others.