 The Covid-19 pandemic has had a significant impact on the female reproductive system. Studies have found that it can cause disruption of the ovarian microenvironment, leading to decreased oocyte quality and ovarian function. Additionally, it can lead to premature ovarian insufficiency, ovarian vein thrombosis, hypercoagulable states, and changes in the menstrual cycle. Furthermore, it can also affect the hypothalamic bituitary ovarian axis and sex hormones such as estrogen, progesterone, and antimalarian hormone. This article was authored by Sohila Pormasumi, Nicholas G. Kunis, Mona Varnaduri, and others.