 All right, welcome everybody. Thank you again for the invite, great organization and for a great day one. So I'll start off speaking about DHS-2 for LMIS, last mile solution, supporting supply chain and health program management. All right, so there's a lot in this title but I'll try to get through all of the different aspects and what that means for using DHS-2 in this use case. And my name is Brenna Horst, working with the University of Oslo Hisp Center as the LMIS tech lead. And I'll give you an introduction on that as well. So for this session, I'll have a short introduction. I'll go through the DHS-2 LMIS approach, about nine slides there, but really important to get a background of what we can achieve and what we recommend as best practice. I'll go through the overview of the specific features. There are quite a few slides, but many screenshots there and that will really just be a snapshot of what can be done. And in the afternoon, there will be a session where we can do more hands-on and I can answer specific questions. And I think session three will be a good starting point for that. One single slide on guidance and resources, just with some quick links, which you can then also go into the presentation and follow up on those. And then a short summary as well, only three slides there, but giving of closure to the discussion and why we present this as our approach. So for the introduction, I'll share a global team perspective. So the perspective from the HISP Center, seeing how DHS-2 has been used for collecting stock, coal chain and other LMIS related data. And this will be our perspective across the field, both within DHS-2, but also touching on a few other tools. And then it's to receive feedback and launch this discussion with all of you because your feedback is really important. It's not that I'm presenting this as the only way, but it's what we see as best practice, but your feedback, your perspectives are essential to making a useful and relevant use case for your work. So as part of the introduction as well, myself, Brenna Horst, LMIS Tech Lead. I work closely with technical advisor, George McGuire, who has many years and lots of research experience working within health supply chain. We're also having support from Per Kronzler, who's a supply chain advisor. And then we have two dedicated members in different HISP groups who are then working with implementing the use case and developing this further. This is in addition to all of the different members within the HISP Center working on developing the use case. So now for the approach. And this is, again, what we see as a reason for using DHS-2 within this use case. And we oftentimes get pushed back from other vendors, from other developers developing other tools. Why is DHS-2 going into this field? And here just to give a snapshot, and this is an overview from a World Bank Health Information Systems paper where LMIS is shown as a part of the HIS landscape. We're not looking to do logistics for the sake of logistics, but really to contribute to health outcomes and looking at how it fits into this overall picture. So this is really the focus. It's not anything more than contributing to a foundational aspect of health service delivery. And then DHS-2, of course, you've seen this before, where it's been implemented globally and increasing. This is also another very strong aspect. And I'll relate this back to the other tools, the LMIS tools that have been implemented. None of them have the same reach and the same success as DHS-2 has had within HIS and HMIS. And this then means that there's a lot of competence, a lot of infrastructure, resources, capacity with using this system. And that can be leveraged for capturing stock data in a specific way, which I'll explain further. But it's leveraging all of this capacity, all of the knowledge that all of you have and you have within your countries to then bring in data that's not being captured in any other way. Also on the approach, we looked at the practice and again, how DHS-2 was being used, but then we also wanted to have some standards and looking at what do the standards say about health supply chain management and stock management, also cold chain. And these are two key documents which we've used. And I think the most important one that I would refer to is the target software standard for vaccine supply chain information systems. And that was recently revised, the second version released earlier this year by the Interagency Supply Chain Group, which is made up of all of the major donors supporting our work. And some of the key aspects end-to-end visibility within the national supply chains. So from a central medical store down to a facility, having real-time data, so how much do we have of which product in which location right now? Capturing both transactions and being able to provide reports either monthly, quarterly, or so on reports. Interoperability with the health information system, which in a sense is an easy one for DHS-2, being that the health data is there in the same system. And then some cold chain monitoring and cold chain features. So those are the key aspects and they go into much more detail in the document, of course. And then as part of our resources and there's a link within the presentation as well at the bottom right, which you can click with the comparison of the specific features, specific requirements, and then a explanation of what DHS-2 can or cannot provide and an explanation why. And you can even comment on the document and ask us questions, why can we not do this or that? Why can we not use DHS-2 at a central medical store? And we can give explanations and elaborate on that. But this is a very key reference document when discussing requirements and functional requirements for what you're aiming to achieve by using DHS-2 for stock management. Now to give you a snapshot on this functional requirement perspective in the national supply chain. So if you take this first part here as the central ELMIS or ERP, so a central system managing supply chain, and then you have your last mile tools, this is the functional features within a facility level. You have a very extensive and this is really a small list of different requirements that this tool would need to provide at a central medical store state level down to district. Everything from procurement to warehouse management and really large scale warehouses when you're talking about a central medical store, transport tracking and many other features, not the least of which demand planning and forecasting which ensures that you have the supplies you need throughout the chain. What we focus on and what I'll elaborate in detail are the features then for stock management, two different options there for cold chain management, the analytics and a simple product catalog which we've now developed and we have available to be used within DHS-2. Many of you are already capturing stock management in one way or another, so it's partly already there but those are then the features that we would recommend to use for DHS-2, ELMIS and which I will elaborate on. I'll have another slide on considerations before but it's important to keep in mind what the scope is of implementation, what the features that you're targeting and the reason for that and I think scope creep is a very real risk when discussing this. That small detailed box suddenly increases when you start implementing and then it starts taking space up here and I think that's something we need to guard against and understand exactly why we're doing what we're doing. Now to give a quick overview of the data integration model or the data being used as a very generic representation of a health structure within the country, if you have your health information pillar on the right with the DHS-2 being used at multiple levels for capturing and analyzing data for the logistics data or logistics information here on the left, we're only looking at the community health worker, hospital, health center, really the service level of the supply chain, we're not looking to implement at a central medical store or even down to a district store, those really we recommend using a dedicated supply chain management tool like an ELMIS or an ERP and we have multiple examples of this being done but having this integration through an interoperability layer or point-to-point integration between the systems and that way covering an end-to-end supply chain requirement that we aim to achieve and also the standards asked to be met. Now, people ask why not just use a tool dedicated for supply chain management in all of the facilities and this is just a very, very small number of tools. There are really hundreds to thousands of different tools being implemented if we look at the global landscape, oftentimes in parallel for specific programs and none have really attained the same reach that DHS-2 has as I already mentioned and what we're looking to do is then supplement their capacity at a central level to reach the facility level. They all have their strengths and weaknesses for different reasons. Some of them, if you go to the right side with Oracle and Sage, you have very expensive, very resource-demanding tools that require completely restructuring and organization processes to fit their model to then very flexible tools but maybe with slightly less features than you would have with the full-scale ERP. One of the vendors here that we're working closely with and which maybe some of you are familiar with is M-Supply. They're based in New Zealand and they have quite a few implementations in Asia and there are already 20 years in the field so they have quite a bit of experience. They're migrating to an open source solution so they'll be making their code available and their existing implementations should be migrated to an open source as well and we've been developing a closer collaboration with them and we'll even be providing some guidance, publishing some guidance and next week holding a webinar so I just take the time to promote then this webinar which will share the invitation to all of you so you can see how a functional integration can actually be made with the M-Supply tool to be able to provide this end-to-end supply chain management. Right, so that's the overview of the different tools and then as I've hinted upon a few times already in the presentation, DHS-2 can support multiple different solutions within this facility level stock management and cold chain management but there are certain considerations to take and I think this is important, I'll touch on these but we really need to elaborate them on a case-by-case basis because supply chain management policies will vary from country to country. The way that these structures are set up to distribute medicines and products throughout the country will not be exactly the same and that needs to be accounted for. What we then can say as a starting point is that we can support multiple structures and policies but we promote holistic supply chain management so having all of the products within one system and not having this siloed parallel management with maybe one tool for one program and maybe paper based in Excel for another and DHS-2 for for yet a third and this is something that we clearly see happening so we really promote and aim to answer to this holistic management. Another one is order management and we would promote strongly VMI vendor managed inventory something you can discuss with your supply chain teams not used everywhere but this puts the ordering demand planning in the hands of a central store or a district store rather than having individual facilities making individual orders with varying levels of competence so it's really about putting that requirement and technical competence within the hands of a store that should have better capacity than the individual facilities. Residual stock count for counting stocks at a facility store or at a medical store and I'll go into that slightly later and then the importance of having facility level consumption data how much is actually being used and not speculating on the number of items that were sent in a previous order a previous month or the previous six months it's knowing what the actual quantities that have been used are and I'll refer also back to that much later because you create this demand distortion based on the system dynamics theory that then gives a small signal down in the supply chain will give a very large distortion further. Last point on the considerations and I'm really bringing this up because it's important to not jump into a solution before really understanding what is behind if we simply look at stock replenishment so how do you calculate orders for your facility if that's being done through VMI or orders coming from a facility level you have all of these components to build your stock order how much stock do you have on hand what is your average demand and you can take previous month previous six months or previous 12 months what's the lead time how long does it take for the goods to actually arrive what are your safety and buffer stocks and you can work in all kinds of different variables in there based on seasonality and how these variations occur and the key aspect is to understand what is happening behind each one of these points if you happen to have a wrong lead time there's no system that can overcome that the system will only ensure that you have a guaranteed stock out or overstock situation because one of the variables are not properly set so having this understanding before jumping into finding the digital solution I think is really essential and what we would like to then engage with is what is behind the policy first and then how can we use the digital tool to improve that I think considerations is something that we should spend a lot more time on before going forward with actually looking on how to implement all right so that was the approach and how we see the tool best being used and now I'll go into the specific features and what they look like all right there will be a lot of screenshots screenshots of the different data entry screens and so on but we'll have a chance to try it out on a tablet in the afternoon where I'll be speaking to you in a parallel session one point here we're looking to use native DHS2 functionality first that means that we're looking to develop different use cases that can be immediately used and not requiring newer versions or further software developments and of course the first is the aggregate data model and monthly reporting I think this is used in quite a few countries long before myself and the LMIS team came on the scene that stock data was already being captured it's a great step to digitizing really stock reporting making this data available if you have your requirement to report data by the seventh of the month you can also have your stock data available by the seventh and that can be used for replenishing stocks that can be used for informing orders and reducing that demand distortion that I refer to if the stock received the stock on hand are all up to date it's the best indicator of a correct order and ensuring that you have the correct supplies to treat patients that need the treatment a lot of times you have these physical paper stock cards and this is what we're looking to replace is to have the reports immediately available by digitizing this aspect of the inventory control so that was the reporting secondly is then real-time stock so one of the requirements from the standards and what many people ask is can we have real-time stock and this is a tool that was developed in version 40 released earlier this year and from Android Capture version 2.8 Austin referred to it yesterday and this is the specific workflow for issuing medicines or products within a health facility with just three or four clicks you can choose the distribution workflow the facility that you're working with and where that is being issued to and then you have an immediate list of the stock on hand and how much you're going to distribute this is a tracker program there's nothing different than what's already able to be configured on tracker but with the regular workflow it would be 14 to 15 clicks to issue a single item and that process would need to be repeated for each one here you can issue multiple items with much fewer clicks and again that's what you'll be able to test out in the afternoon so it uses residual batch counting you can immediately put the number of items that you're taking from stock and you'll see the remaining quantities and you can count how many is on your shelf and just match those numbers it replaces the physical stock card with the line listing so the line listing app will be able to show how much stock you have and what the transactions have been you can use for the stock received you can either have that through an integration or using a bulk load or import tool and the barcodes can be printed for barcode scanning for issuing and then for future development it's the ability to manage items at a batch level and even a serialized mode for vaccines when those requirements come into play and GS1 data matrix codes are incorporated in vials so that is the next iterations of this tool it does require that you have orderly stock with the different barcodes at a generic level for the different items these are images actually from an implementation in Yemen still at a prototype phase from a COVID-19 treatment clinic in 2020 but it's simply a requirement to have orderly stock with barcodes and this could be done in a larger or smaller facility and here you have, I'll go through some quick screenshots just to show the workflow and how that looks so you go into your Android Capture and you have your program for your real-time stock management at the top you click on that and you're given this specific workflow which is activated for that one program for stock management the distribution workflow here is chosen you're already assigned the facility to where you're working and you can choose where to deliver so in this case, inpatient surgical departments the items that are available with the current stock on hand are shown you choose the quantities you want to take from stock chloroxidine two and so on and you click a review button at the bottom you simply confirm that the quantities are correct you look at the table, you've picked your items and now they're there in front of you yes, 188 of this item, 41 of the other and you click confirm and that is, your transaction is complete as soon as you synchronize your device that information is immediately available for the upstream system in the case of an integration or for any reporting or any information within the DHS-II system second transaction then, second workflow you click on your real-time stock tool you choose discard now instead of distributing, we're going to discard this is in the case that you might have an expired item or a damaged item you then have a color code change so you really know that it's a different workflow you choose the quantity of items you have the same review and confirm and that workflow is completed in the same way as the first and then the last workflow that we're supporting is stock correction and this really is in the case of once you conduct your monthly stock count you count all of the items that are in stock you see that there's a difference either stock found under stock loss you can then correct that quantity with this third workflow and with these three workflows you're then ensuring that you have your accurate stock on hand in a very simple workflow for a facility level worker who does not have stock management as their number one or two responsibility many different priorities lots of different work to be done and this is a simplified workflow to be able to capture that information all right so those were the first report-based and now transaction-based stock management I move on then to equipment or cold chain equipment, life cycle management so this is another tracker-based tool and this is to manage and update cold chain equipment inventories using tracker you can capture all of the different cold chain equipment within facilities from the moment of installation all of the different stages within managing that repairs, preventive maintenance, alerts and any other event all the way down to the end of life and once the equipment is no longer in use and in that way you have an immediate global or national catalog for all of the item that you have currently being used it's integrated with the WHO PQS catalog so you have these different attributes immediately populated once you're registering and enrolling your equipment and it can support decision-making for vaccine distribution knowing the equipment that you have if it's in functioning or not and also for strategic planning for replacing items you can quickly see where you've had more alerts where you've had more repairs required and which pieces of equipment require replacement and this is just a simple graphic showing the number of alarms this is just a demo data it's not from an implementation showing different areas that have had more or less alerts and in this way you can target where equipment needs to be replaced as part of a replacement plan another thing, we'll also get to test this out in the afternoon another thing that can be done is that repairs can be requested so a facility can actually request for a repair and a notification sent to a district technician who then within the line listing app can have all of the different requests by facility and in that way plan their regular work to ensure that all of this is online again the same can be done for biomedical equipment or really any kind of investment material here for hospital management you can have all of the different pieces of biomedical equipment within the hospital with the specific stages that are needed for that piece of equipment not all of them will be the same of course for cold chain you have different considerations temperature monitoring and so on so that can be adapted for the type of equipment also that you're monitoring within a hospital setting temperature monitoring this is one which is under development we've developed a prototype we've run a pilot in Mozambique where we actually connected a Bluetooth sensor to the Android capture and had that data within DHS2 it will be a future requirement again according to the WHOPQS and something that we want to be ahead of the curve if anybody is looking into or interested in discussing this further it would be very interesting to see what would the specific needs be and if you have any experience within the use case what we're looking to do is make a solution that would be readily available for any type of monitoring device that might be available out there so we're looking for partners interested in developing this together with us so for the first tools that I showed you they're available ready now to be implemented and used for this we're still developing further this temperature monitoring concept what can be done is manual data entry rather than inputting the data on a paper form you can move that to entering it in the tracker connecting it to the equipment life cycle management and in that way you're digitizing again your paper forms but this would be the then future iteration with automated temperature monitoring and then last but not least is just a simple product catalog available for health workers so once the products are being managed at the facility level with the real-time stock management you can also have different products with the attributes and details of that available for the health workers now for the integrated dashboards on web or mobile just the ability to provide analytics and compare health and stock data side by side can also provide a lot of insights and this is another aspect again going back to the standards and really practice showing how much stock has been used and how many patients have been treated and seeing if there's any discrepancies between those can also inform decision making improving health service delivery and so on for that we have a specific project which we've worked on called the Thrive 360 project with UNICEF where we've brought in some UNICEF and country supply chain data not very many a lot of it is survey data and then compare that to different service data within DHS-2 and this is really to support national logistics working group so the joint immunization supply chain teams to be able to analyze and conduct operations with information in one single source many times these teams are accessing different websites PDF files locally Excel sheets that they track waiting for paper forms and reports and the objective of this and what we've done is brought together multiple sources into a single system and they're calling it the national control towers for immunization supply chain and we're running actually the first trainings and the first pilot countries to really connect to these teams and see how having a singular place for all of this immunization supply chain data can support decision making and operationalization so that's for the analytics aspect for any of you working closely with UNICEF we can also see how that may be interesting to be implemented and they're looking to expand that and make it available for all UNICEF supported countries so that was a very quick run through of the features so stock management, coal chain and biomedical equipment life cycle management as well as the product catalog and the developing temperature monitoring for all of those there could be many considerations and I think that's what is really important for us to focus on in the parallel sessions in the afternoon getting your feedback and getting really the details of what the use cases may be one of the key points as well with the considerations is the ability to bring in the LMIS perspective the supply chain perspective into the discussions now for guidance and resources it's a lot of the same resources you're used to so within on the dhs2.org website you have a logistics page that's dedicated for that if you navigate through the health domain you'll be redirected to the logistics page if you look at stock and coal chain of course so very much something that's integrated in that sense the configuration for these tools are available on the documentation website at docs.dhs2.org the community of practice has also a section under implementation for supply chain and LMIS so feel free to go in there ask questions and challenge also our approach challenge this best practice that we're showing and come with new requirements and really that's the key to improving I think is having that feedback and then we also have a demo site where you can go in and play with these different tools and see how they're actually functioning and use them as a reference point for your discussions now I see actually that I'm a bit ahead of time I had to cut down a much longer presentation to be able to fit the 45 minutes but I think that's fine we can maybe take some questions but I'll move to the summary then section so improving health program management it's the case that I made at the very start showing that landscape the HIS landscape and really looking at what can we improve and really we're looking to improve the health service delivery and looking to bring in stock and health data for analytics and then looking to improve the availability to improve the outcomes the health outcomes secondly and the concept that I refer to multiple times is the demand distortion within the supply chain having that key consumption level data for the demand planning and the distribution network is essential to reducing stockouts and overstock I think stockouts are commonly referred to as the number one challenge for health supply chains when speaking to different partners it's the number one aspect that they bring up and I think this is one of the key aspects that we then want to leverage with aiming at facility level data another point here is once you have that facility level data we don't simply want to show beautiful charts and beautiful maps with here are the stockouts we have you need to make that move to operationalization connecting supply chain teams and operational teams to be able to first identify and then immediately rectify stockout issues and making that jump is oftentimes more difficult than it may seem so it's not simply about showing the problem but how can we actually connect this to decision makers there's no sense in making it available if the teams that can actually do something about the stockout that they don't have access to the system for example so making the connection with LMIS teams giving them access to the system the Thrive 360 platform as I mentioned in the UNICEF project it's about putting the data in the hands of those that can actually make a difference and rectify the situation and then my last slide on the summary is again reinforcing that logistics management here we're proposing it as a subset of health and should be aimed at improving health outcomes that is the overall outcome within LMIS then DHIS2 can be used at the facility level in a very effective way and we really try to link how that can be used to the outcome level consider all of the same aspects of good HIS design user centric participatory design and so on if you're creating dashboards and wanting to show stockouts because there's a top manager wanting to see those that's one aspect but if the data is not available for the user that can actually operationalize it it really isn't achieving your overall outcome and I put there think of yarn I know many of you have referred to his teachings and the advising so keep him in mind in that aspect we're not advocating for anything different than what you've been doing before and then the second to last point on implementing LMIS tools without foresight may create more problems than it solves I had two slides on the considerations and really it could have been a hundred slides the number of discussions we've had from country to country from a partner to partner the different aspects that go into the solutions are can be quite complex and they're both organizational and technical and those need to be explored on a case by case basis the policies used for demand planning for supply planning having public and private facilities or paid or free products there's a whole lot of complexities that go into this I know that dispensing to patients is one requirement that is often asked for financing and accounting how much does this do these products cost how can we report on that how can we link all of this together and we're very quickly the scope creep going into the ERP-ELMIS tool how do we do everything and that becomes part of the challenge is having the foresight to say we're aiming for this objective and then keeping it at that level and for the additional use cases developing them maybe one by one and again that's where I ask that you challenge us on how we can develop certain of these use cases a bit better and maybe a bit broader but for now this is really a key aspect the considerations and then lastly it's a question back to you if it's better to join forces and provide an integrated end to end solution for LMIS don't try to do everything with a single tool simply using the ELMIS that are available has been very successful in certain aspects but there's none that's had the same reach and success as DHIS2 within HMIS and that's what we try to propose here is that integrated we may be able to have that reach look at supply chain manage in a holistic way across products across programs and then also look at how to reach all of the different levels of the supply chain having an expensive tool at a central medical store and distributing down to a district store is needed and important but maybe the cost effectiveness of then rolling that out to hundreds and thousands and even tens of thousands of low level facilities may not be as cost effective so then having DHIS2 integrated at that level that's really the key that we're trying to unlock and show that there's a cost benefit here to using it at that facility service level many facilities with some low resource or at least low volume and having the data then digitized across through the integration model all right I see we have quite a bit of time for questions I went through perhaps a bit quickly and I even as I said removed slides that went into more technical details and challenges that have come up but maybe if we can take questions or hear back from the group I think that would be great but that's DHIS2 LMIS thank you Good morning, dear participants and thank you for such a great presentation as a manager of the immunization program as a manager of the immunization program I want to say that this is a great news because in the initial versions of DHIS2 of course LMS was not present as we knew and at the moment that there is a good approach and use of universal DHIS2 LMS this is a unique opportunity Thank you so much for a very nice presentation for a very informative one and it's a great news that finally LMS can be integrated with DHIS2 because as far as we know it was not integrated before and it provides great opportunities from the perspective of the immunization program that is to say generally for the immunization program this is a cold chain and the control of the reserves is one of the, let's say, priority also in the direction therefore in 2018 in the 19th years Kyrgyzstan conducted such a let's say it was a UNICEF mission a country that considered the possibility universal DHIS with elements or integration of LMS and when we made such a transition it turned out that it will be very expensive but if now DHIS2 will sit such a function exactly that with LMS it will be a great opportunity for the country So actually from the perspective of the immunization program both the stock management and cold chain equipment management do represent the priorities and back in 2018 and 19 UNICEF has already invested some efforts into trying to integrate the LMS and DHIS or at least some elements and there was some costing exercise conducted but it turned out to be too costing and that's why we're very happy that now this opportunity is becoming closer and Kyrgyzstan will make the presentation and probably that will be the time when they will all elaborate on these elements but since or due to the shortage of this integration of LMS and DHIS2 the Kyrgyz Republic has developed separate modules for stock management and cold chain equipment management in the overall health information system and since you have presented the functions or functionality of this new integrated approach Gulnara has a question whether there will be also the opportunities to support the inventory of the vaccines as well because there are some nuances and we have faced some challenges with as far as the inventories concerned not only the stock management but the inventory as well Can I ask what are the different nuances about the inventory apart from the stock control what exactly is the difference that she refers to First of all, I would like to inform you that there in the Kyrgyz Republic we have four levels of vaccine supply at the national level original level district level and health care facility level and we had some challenges related to the or associated with the delivery of health services or vaccination or immunization services first of all how would it be possible to manage the inventory and the stocks at the facility level after the services are provided We are working on this This is the area that we are working on Okay, great Thank you for the information I think we'll have a lot to speak about and discuss the specific use case What I think is interesting is we're looking at supply chain management from really the demand network and how the stocks are distributed from central medical store to the last store at the service level and really that's what's comprised with what I presented exploring the use cases beyond the store once it's issued from the store I think that's where we want to have those considerations discussions What does that entail? Who is involved within that workflow? If it's in an immunization program is it vaccination teams? If it's in a clinical setting is it a doctor prescribing and a patient is picking up the items? So it's extending the use case beyond the medical store which I think is the considerations discussions which should be taken on a case by case basis and secondly that we're very happy to then receive those requirements and then that we're challenged on improving how that can be solved So we'd be happy to discuss and take this up later on in the day So thank you Thank you Thank you so much for the for the answer and another short question promise So what are you using the sizing double-hitch sizing tool in your work and web based cold chain equipment tool which is called EGA EGA Yeah we've been in close collaboration with UNICEF and WHO and other partners We've looked to align what we're proposing with what they have part of the approach also I didn't I wasn't so explicit but we don't want to duplicate existing solutions We're not looking to go into the space where yeah the EGA and there's also the WHO SMT tool and there's there are many other tools and I even showed some of the ELMIS We've engaged with every one of the ones on the screen that I showed and others and we're looking to develop tools that are not existing or widely implemented and that goes for all of them So we're looking to be aligned with what's in the market and fill an existing gap All right thank you everyone and I'll hand it back to the to the organizers Thank you All right I'd like to ask my colleague Michael to come up now he wasn't here with us today so before he gets started I'd also like to ask him to make a bit of an introduction about his role and what he's doing with us in the the university