 This study evaluated the effectiveness of a competency-based job framework in reducing employee turnover in a large, clinical research-intensive academic medical centre. The results showed a decrease in turnover from 23% to 16%, representing a 45% reduction. This suggests that the competency-based job framework may be effective in reducing turnover in clinical research settings. This article was authored by Maurice Astru, Curable S4, Christine Dieter, and others.