 This study aimed to optimize the microwave-assisted extraction of cataphalophica using a box-banken design. The three main factors examined were microwave power, time, and number of cycles. The eight responses measured included extraction yield, total phenolic content, gallic acid content, carillagin content, chebulagic acid, chebulinic acid, DPPH radical scavenging activity, and ferric-reducing antioxidant power, FRAP. Additionally, cytotoxicity tests were conducted to ensure the safety of the extract. The optimal conditions for extraction were found to be microwave power of 450W for 30 seconds and 3 cycles. The resulting extract exhibited high levels of total phenolic content, gallic acid content, and antioxidant activity while maintaining a safe level of cytotoxicity. Finally, the optimized extract was compressed into tablets, which were successfully produced at a compression force of 1,500psi and magnesium stearate of 1%. This article was authored by Chowlett-Monten, Piapakiche, Chantisa Pakrong, and others. We are article.tv, links in the description below.