 Romatic diseases are a group of inflammatory conditions that affect joints and connective tissues, often accompanied by pain and restriction of motility. Autoantibodies develop in many of these diseases that react with molecules structures commonly found hidden in neutrophils. Neutrophil extracellular trap, net, formation and release is considered a defense mechanism against pathogens or endogenous danger signals, but if not timely removed from the crime scene, it might modulate subsequent immune responses and contribute to the pathogenesis of chronic inflammatory diseases. This review summarizes the multifaceted roles of nets in the etiology and pathogenesis of rheumatic autoimmune diseases. This article was authored by Melgorzata Justina Podolska, Apana Mahajan, Jasmine Knopf and others.