 Brutongue is a fascinating disease. Let's assume that all these sheep in this pen would get infected, only some will get actually sick, one or two might even die, but most of them will have just a bit of a fever or be completely healthy even during infection. So how is it possible that the same virus can kill infected animals and just cause basically nothing to another one? And that's what we're trying to understand. We studied both the virus in vitro and in the animal in the field and what we hope by putting all together all this data that we have both in vitro and vivo, how the virus cause disease. The emergence of a variety of arboviruses in the last 20 years like dengue, chikungunya, ziga allow us really to use this animal model to learn lessons in viral pathogenesis that can be applied to other diseases. So it's important for animal disease and human health.