 This study examined the co-digestion of two waste streams, organic fraction municipal solid waste, OFMSW, and biological sludge, to determine the optimal conditions for methane production. The biochemical methane potential, BMP, test was used to measure the methane yield over time, while other methods were developed to reduce the cost and time associated with BMP testing. These included a model based on the elemental composition of the waste stream, which predicted the methane yield more accurately than the BMP test, and a model based on the Gomperts curve, which could predict the methane yield after seven days of experimentation. The study found that the optimal co-digestion ratio was 80% OFMSW and 20% biological sludge, and that the methane yield reached maximum levels after seven days of experimentation. This article was authored by Anilfa, Arkano, and MFDZ-Polanco.