 In the representation I talked about the disease and treatment related side effects in multiple myeloma. So there are a lot of disease and treatment related side effects, so I couldn't discuss them all, so I chose four of them. So the first disease-related complication I talked about was bone disease. So it's really important that even if patients don't have osteoarthritis at diagnosis, that they will be treated by phosphonates or the nose map if they have renal impairment just to prevent bone disease. So the second disease and also mostly treatment related complication was peripheral neuropathy. A few treatments like tildemite and botanism they give peripheral neuropathy and we don't have preventive treatments to prevent the people that the nurse will be damaged. So it's important when people experience some complaints like tickling or numbness in their both hands or both feet that they discuss it with the physician. So that's depending from their complaints, like if they have problems with riding or opening the bottoms of their shirt, that we need to adapt the therapy because it's important that we early adapt the treatment to prevent that the peripheral neuropathy is irreversible. The third, mostly disease and but also treatment related side effect is infection. So patients with multiple maloma are seven times more increased risk to get an infection, mostly from their respiratory tract. So we know out of research that patients who are elderly or have a high risk of multiple maloma or active disease or patients with some organ damage, like renal impairment, they have an increased risk for an infection. So it's important that the health care provider that we do a good assessment and even start some preventive treatments, like if patients got partisan inhibitors that we start a cyclovar. But it's really important for the patient that if they got fever or some symptoms from an infection, that they go to the doctor and that we early manage this infection so that they don't wait a day, they need to go directly to the doctor. The fourth disease related complication out there I talked about is also fatigue. 90% of the patients experience fatigue and one of the myths that a lot of patients on care gives things they need to rest and calm down. And that is wrong. It's really important that you stay physically active but it needs to be well guided. So it's important that we do an early assessment and just see that there isn't an instability of the bones and that it's safe to do some exercises. But there are a lot of exercises that we can do like doing a walk or do some that we can exercise the muscles like doing some squats without some weights. Just that the body stays active and to improve the physical but also the mental health of our patients and reduce fatigue.