 Hwang et al. report no correlation between the immune response to the hepatitis B virus, HBV, vaccine in newborns and the HBEAG status of their mothers, but draw unfounded conclusions regarding the tolerogenic potential of inutero exposure to HBEAG. The function of HBEAG should be considered known as Immunotolerance Immunomodulation, which promotes viral host interactions. This article was authored by David Amilic.