 This paper presents a methodology for evaluating the economic benefits of infrastructure coordination in river basins, specifically the Mekong River Basin in Lao People's Democratic Republic. The results suggest that coordination can improve system net benefits from irrigation and hydropower by approximately 3-12%, or US2-53 million YR, assuming moderate levels of flood control, and that the magnitude of coordination benefits generally increases with the level of water availability and inflow variability. This article was authored by Mark Jewland, Justin Baker, Ryan Bartlett, and others.