 This paper examined the effects of fluconazole, a commonly prescribed antifungal medication, when combined with various essential oils. Lemon, orange, tangerine, and grapefruit oils were tested individually and in combinations with fluconazole. The results indicated that lemon oil had the greatest effectiveness against aspergillus fumigatus, while tangerine oil had the lowest effectiveness. When combined with fluconazole, these oils demonstrated varying degrees of synergy or additivity. This study suggests that essential oils may be used in conjunction with fluconazole to enhance its efficacy against certain types of fungi. This article was authored by Paula Robles-Kaluxka and Jerin Ulusksky.