 Our recent study demonstrated that an oral cancer vaccine using a recombinant bifidobacterium displaying weight 1 protein had a significant anti-tumor effect in AC1498, weight 1 murine leukemia syngenic tumor model compared to a peptid vaccine. The weight 1 protein displayed in this vaccine consisted of about 70% of the weight 1 amino acid sequence including multiple known CD4 and CD8 T cell epitopes of weight 1. This article was authored by Toshiro Shirakawa and Koichi Kitogawa.