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Uploaded on Oct 5, 2011
Scientists have known for decades that genes called transposons can jump around the genome, but it can be dangerous, especially in cells that produce eggs and sperm. To ensure the integrity of these cells, nature developed a mechanism to quash this genetic scrambling, but how it works has remained a mystery. Now a team of scientists, including researchers at the Department of Embryology, has identified a key protein that suppresses jumping genes in mice and found that the protein is vital to sperm formation.