 10-valent pneumococcal non-typeable haemophilus influenzae protein decondigate vaccine, P-hydCV, is used in childhood immunization programs worldwide and has been shown to be effective against invasive pneumococcal disease, pneumonia, acutatitis media and pneumococcal nasopharyngeal carriage. P-hydCV also provides herd protection for vaccine serotypes among unvaccinated individuals, although there have been increases in non-vaccine serotype IPD and NPC rates. This article was authored by Thomas Merkvan, Stephen the First Pelton, Javier Ruiz Ganazu, and others.