 Adenoviruses are a family of viruses that can be used as vehicles for gene transfer. They are highly efficient at delivering genetic material into cells and have been used extensively in research and clinical settings. Adenoviruses have been engineered to express therapeutic proteins, such as antibodies, cytokines, and enzymes, which can be used to treat various diseases. Additionally, they have been used to deliver genes encoding for tumor suppressors, immune modulators, and other factors involved in the development of cancer. Adenoviruses have also been used to generate vaccines against infectious agents, such as influenza virus, and to induce immunity against tumors. Finally, adenoviruses have been used to generate stem cells and other progenitor cells for regenerative medicine purposes. This article was authored by Kodi S. Lee, Elliot S. Bishop, Rui Xiong, and others.