 This study evaluated the effects of home-based exercise management with a customized mobile app on exercise amount, physical activity, and quality of life, QOL, in patients with Parkinsonism. The results showed that participants reported a significant increase in exercise amount and improvements in secondary outcomes such as IPAQ, PDQ-39, and GDS scores after eight weeks. The usability of the program with the mobile app was verified based on positive responses such as intention to use and role expectation for rehabilitation. Exercise management with a customized mobile app may be beneficial for improving exercise adherence, physical activity levels, depression management, and QOL in patients with Parkinsonism, and is recommended as an alternative exercise management strategy during the COVID-19 pandemic. However, additional clinical trials are needed to evaluate its efficacy in a large population and confirm its disease-modifying effects. This article was authored by Arim Kim, Seo Yoon-yoon, Kwon Sik-sung, and others.