 into the last video and this one. The last video that we've recorded and you can tell it was the last one because I'm wearing the same clothes. Oh, I'm a wardrobe. Dang, folks. And sometimes it just doesn't happen. So anyway, I don't think Avery's gonna come into this video, which is fine. But for those of you that wonder why we let that stuff slide, it's because you need to go back and look at the McSweeney video. Alright, so if you go look at McSweeney video, then you'll see that she was talking about habituation to reinforcers, right? So let's assume that this sort of format might be reinforcing for you under certain circumstances. And if that's the case, it's possible that you'll habituate to us. And one of the things that you can do to mess with habituation and recover sort of the value of the reinforcer would be to produce a stimulus in the environment that's largely just random. You know, one of these things. Avery may have served as a disabituator. We don't know. Maybe the cards are a disabituator. We don't know who knows. But all we know is that after nearly 800 videos, we haven't done much to disabituate you. So you might expect us to do something or not in the future along the lines of disabituations. Or we just tell funny stories about really cool journal articles such as this one. Conditioned inhibition of cocaine seeking and rats. And for those of you that think that I have done cocaine and I do it all the time in front of my videos, I do not. But it's one of the things that I don't know how to speak quicker. I can't imagine doing cocaine, because if you can imagine how quickly I speak now, I can't imagine what would happen if I did it. That's what would happen. I would go nuts. Alright, here we go, because this is a quick article, discrimination training for self administration of coke, click tone, and something else. Oh, and or neither. So sorry, folks, I'm really not on coke. Here we go. So the idea is, this is an extension of some of the literature on drug drug issues, right? Drug seeking behavior. So we need to look at drug seeking behavior first. So what is drug seeking behavior? Drug seeking behavior is when you seek drugs, like I'm gonna go from Oh, drug seeking behavior, I just did it. Why? Because there's drugs in there. It's caffeine. It's great. You know, sans vodka even better. Alright, so in the fact that I'm reaching for that or looking around the room for that's drug seeking. So the moment I grab a drug seeking behavior, right? So you have to engage in drug seeking behavior before you take drug taking baby before you do drug taking behavior, grab drug seeking behavior. I have to grab drugs taking behavior. That's it. I hate it when I use words that I'm up attending to too much cocaine, too much cocaine. Hi, at least I'm not driving trains. Casey Jones, you better watch your speed. Why? Because somebody's gonna steal it from you. We're screwing around on this video, folks. I don't know why because we are. Alright, so discrimination training for self administer. Oh, sorry, I was back there. So we're looking at condition inhibition. And we have to understand that one of the pieces of any drug taking behavior is drug seeking. So you have to seek it before you take it. For the most part, sometimes there's other ways that people can give it to you, I guess, you don't have to seek it. But that's a different issue. The literature as a whole has been focused on I can't keep a straight face when he's back to get close. If drug seeking behavior doesn't happen, what does that mean? There's a guy out there with a gaming NCR just I was thinking more about over a bridge or an airway. Just blow it. Everywhere. Everywhere. That would be the the way to do coke, like in a non drug seeking. Like I didn't seek it. I swear to God officer me just blew it all over me. I don't have powers of white. People think we're on drugs. Before this one, y'all were high like, no, we would just be like this. Because we have very limited. It's probably about five minutes. Now I'm doing nothing. All right, can we try this again? Can we just start over? Like, I apologize for all of you that are paying attention to us at this point. Did our disabituator work? Maybe you did maybe you didn't. We'll tell by the views. It's an empirical question. Actually, watch time. People turn our videos off halfway through. There's a story behind that. And for those of you that know that story, bugger off. Anyway, all right, so that's enough of that crap. So traditionally, when we're looking at drug taking behavior, we'd look at the seagull article that we've recorded a video on before you looking at it from a classical conditioning perspective. These folks we're going to look at it from a different perspective. We are going to look at it from an operant. So what happens if they establish a discriminative stimulus that actually serves as an inhibitor for drug seeking behavior? So we have to think about the type of training that that would happen and I am not going to go through the four pages of descriptions of how they established those discriminations. Because oh my gosh, it was detailed and it was really cool. It was very from what I interpreted very effective. And so did Journal of Experimental Psychology animal behavior processes, which is a pretty top tier journal for Wow. Yeah, anyway, it was a crazy cool procedure. So what they did was they established discrimination training for self administration of cocaine. So the critters self administered coke now is pretty low dose. And they started off on continuous reinforcement, they faded it out. And once they established that they could do that, then they put it on a discrimination training for multiple stimuli. So the click was that something like that. And they had a tone. Alright, so either the click or the tone sick was a discriminative stimulus for the drug, right? So that it's available. And you can compress the lever and get the drug. They had a catheter inserted and it was all it's really cool. Anyway, then they did they have extinction trials obviously. On top of that, once they've gone through all that to establish those things as discriminative stimuli, then they established an inhibited an inhibitory stimuli, essentially, that's minus where they said, we're going to put a bright light in here. And that is going to signal that no cocaine is available. And then they're going to pair that bright light under certain conditions. So if you take that bright light and go by itself, right, you turn it on, no cocaine available. So the rats not going to press the lever because, you know, there's no reinforcer. But what happens if we turn on the sea or turn on the SDs of the click, and the tone, and then the light? What happens? Will that reduce drug seeking behavior? And the answer is, Oh, my gosh, yes. Holy, as I say around here all the time, Holy Spicoli, which the irony of Spicoli and the drugs and it's great. So by training one discriminative stimulus to signal that a particular drug is not available, you can then use that discriminative stimulus and present it at the time that other SDs that indicate that the drug is available. You use those together in conjunction and drug seeking behavior goes, boom, it plummets. The condition inhibition is an effective tool to reduce the drug seeking behavior. So there's a lot of detail in here. And I want to talk about that right again. But I want to read to you the best interpretation of this article by incorporating conditioned inhibitors into q exposure therapy. Pause q exposure therapy is the stuff that you look at the seagull article, all that stuff. So go back to launch the video on that or pull the seagull article from 1975 and you'll see and then follow the research trail around that. So by incorporating conditioned inhibitors into q exposure therapy, practitioners could potentially improve treatment outcome by providing the client with a means of dealing with still active drug related exciters. Here's a tool you can use to help you reduce your drug seeking behavior in the normal context in which you live rather than having to change everything about the context, which is always a problem when you look at treatment of drug seeking behavior, drug taking behavior. The conditioned inhibitor might be a small and portable object, or perhaps a specific phrase or thought that the individual could deploy in situations that produce drug craving by suppressing this stimulus elicited drug craving. This conditioned inhibitor could help attenuate drug seeking and thereby avert relapse. No one says it better than that. I can't say it better than that, which obviously means no one. It's pretty cool. Like again, here we go. Rats jumping over into the real world of cocaine drug seeking behavior. Yeah. Oh, don't forget your AB literature, folks. We've talked about it before. I'll talk about it again, probably a hundred more times. But oftentimes in the applied literature, you can't do experiments like this. Okay, so you can do this experiment with rats. And then you can test the effects to see if it generalizes to humans when you're out there in your practice. This is the evidence that you might need. So one more thing that I wanted to talk about with regard to these people. Holy cow. When they talk about the apparatus, man, the difference in control of an experimental analysis paper versus an applied paper, they're talking about literally what type Tygon tubing from Saint Gobain performance plastics in Akron, Ohio, extended from the 10 milliliters syringes to a 22 gauge rodent single channel flip something apparatus by Alice King. I can't read that. Something medical arts and author in California. Like, there's so much detail in here. And that tells you the level of control that you need to have in order to do genuine experimental type research. So anyway, cheerio.