 Plasmodium, a single-celled protozoan parasite, requires proper chromosome segregation during its male gamete development in order to be transmitted through mosquitoes. In this process, the parasite's Eb1 protein binds to the ends of microtubules, allowing it to maintain a stable connection between the spindle and the kinetocore. Without this connection, the parasite cannot complete its schematic development, resulting in a lack of successful transmission. This article was authored by Xu Xinyang, Minyar CAI, Jun Jiehuang, and others.