 The objective of this study was to investigate the effects of different types and frequencies of physiotherapy on ventilator weaning among patients in the intensive care unit, ICU, and to identify the optimal type and frequency of intervention. 24 randomized controlled trials were included for systematic review and 15 out of 24 articles were analyzed in the meta-analysis. Early rehabilitation, especially the progressive mobility treatment exerted an optimal effect in reducing the ventilator duration in patients in the ICU. Standardized mean difference, SMD, equals 0.91, 95% confidence interval, CI, equals 0.23 to 1.58, P less than 0.01. Regarding the treatment frequency, the high-frequency intervention did not result in a favorable effect on ventilator duration compared with the moderate frequency of treatment, SMD equals 0.75, 95% CI equals minus 1.13 to 2.64, P equals 0.43. Therefore, early rehabilitation with progressive mobility is highly recommended to decrease the ventilation duration received by patients in. This article was authored by Ruiyan Wu, Huanjiya, Kaijia Chang, and others. We are article.tv, links in the description below.