 Botanicals have been found to have potential applications in treating the SARS-CoV-2 virus. These include the use of phytochemicals and medicinal plant concoctions for prevention, as well as the ability to disrupt the virus's entry into host cells, blockets RNA-dependent RNA polymerase, inhibit 3-chymotrypsin like protease, main protease, neuraminidase, and other enzymes involved in virus replication. Additionally, botanicals can act as immunomodulators and adaptogens, which can help reduce the severity of symptoms and shorten the duration of the illness. This article was authored by V. Dushenkov and Adushenkov.