 Namaskara, I am Dr. Basavaraj Kuntoji, consultant, physician and intensivist, Manipal Hospital, Malaysia. I will be talking briefly about the present third wave of COVID infection that what we are all facing and we are also worried that whether it is a omicron and how does this genomic omicron also behaves. The firstly when the patient starts having symptoms and as a doctor when we start seeing the patients, we will not be knowing what is the genomic sequence of the patient. So hence let me discuss in general about the COVID infection as such and then I will briefly talk about the omicron variant also. As we all know the symptoms are the same, the patients may have the fever, throat pain, cough, body pain, headache or the predominant symptoms and yes we do still see patients who are having loss of smell and loss of taste even in this third COVID wave also. And once somebody starts having these symptoms and signs, then we need to do the appropriate test also especially when we call asymptomatic or mild variant, they generally do not need any further investigations at home but however if they have got mild to moderate infection. What I mean by mild to moderate is if they continues to have persistent fever beyond 1 or 2, beyond the third day, if they start having the oxygen level dropping less than 94 percent, then these patients needs to be subjected for either the biochemical blood test and if required the X-ray or the CT scan after fifth or sixth day of their presentation. And based on their clinical signs and symptoms, based on their oxygenation, based on the X-ray or CT findings, we classify them into mild, moderate and severe category. The coming to the mild category at home, the treatment will remain same as the symptomatic treatment giving them paracetamol if required if this if we suspect there is any bacterial associated infection then the antibiotics can be added, vitamin C and zinc tablet also can be considered. Here we feel in case of mild variant, if they continue to have fever, if they are having, if their age is more than 60 years, if they have got a risk factor such as diabetes, hypertension or any immunocompromised state in them, there is a new world risk which are available in the third wave like these are either we can subject them treatment with either antibiotic, I mean cocktail antibody treatment or a newer drug which has come as mulipiravir, but however we need to consider its risk and benefit ratio also. And even the remdesivir also in few of the very small centre studies also they have used in case of mild variant use of remdesivir. So these are all the antiviral medications which has to be used within 5 days for the mild or moderate cases. According to the moderate or severe cases, these patients need submission to the hospital and the drugs of choice as of now we still continue to use either the steroids or the remdesivir or the anticoagulants and sometimes the IL-6 inhibitor such as tosyllysimab and itillusimab can be used. So these are the various classifications of the COVID presentations what we are seeing even in the third wave. However more and more patients are getting involved especially in our anger age group may be at 20 years, 30 years, 40 years and the elderly individuals also are getting affected and they are requiring more of admissions than compared to the anger individuals. With respect to the prevention of this third wave COVID infection, the general precautions remain the same. I would advise not to travel, I would advise to wear a mask, I would advise not to get into the individuals where there are too many groups of people are there and it is a false belief now that even the patients who are taken a two dose vaccines they are still getting infected with the COVID-19 infection. So hence it should not happen that I have completed two doses of COVID-19 infection. Hence I will not get the third wave of, hence I will not get into the COVID infection in the third wave. So hence even though you have taken a COVID vaccine you should avoid getting into the groups, you should avoid getting I mean travelling and you should wear a mask, you should maintain a safe distance and whenever the symptoms starts you should isolate yourself and get tested from the doctor is what I would advise. Into the Omicron variant as I have told you at the beginning we as a patients or the doctors will not be knowing what is the genomic sequence when they start having symptoms and signs. But only when the genomic sequence is done then it will be confirmed that it is Omicron variant. What we have got an experience from the other countries is that there is high possibility that infection rate is very high there are less chances that it can lead into the severe variety but however there are patients who get into the ICU also, who get into the severe infection also hence the precautions always helps to prevent this infection. As well whenever there is a mild moderate variety when initial symptoms are there it is advisable that you need to consult doctor rather than thinking that I will be alright if I wait for a day or two day. So these are my thoughts and advice with respect to the third wave of COVID infection. Thank you.