 Gallic acid is a natural phenolic compound found in fruits and medicinal plants with several health-promoting effects, including antioxidant, anti-inflammatory, and antineoplastic properties. It has therapeutic activities in gastrointestinal, neuropsychological, metabolic, and cardiovascular disorders, but available data are limited to cellular and animal studies, and future investigations are necessary to further define its safety and efficacy in humans. This article was authored by Nilofar Kakashani, Fateh Mefarzii, Maryam Fotuhi, and others.