 Sildenafil, Viagra, a drug commonly prescribed for erectile dysfunction, can be used to treat cholestasis-induced lung injury. This study found that Sildenafil can reduce inflammation and oxidative stress in the lungs of cholestatic animals. These results suggest that Sildenafil may be a potential treatment for cholestasis-induced lung injury. This article was authored by Mohammad Mehdi Amadi, Narjiz Adli, Mehsam Faroozi, and others.