 Kipes-3 is an improved online service that automatically annotates and analyzes biosynthesis pathways in a large number of plant species, including Arabidopsis thaliana, Capsula grandiflora, Dioscoria dimitorum, and Docus corota. It can identify core players, decoration steps, and transport candidates in the flavonoid and carotenoid biosynthesis pathways. This article was authored by Andreas Rempel, Nancy Chaudhury, and Boas Pucker.