 The study investigates the published literature on medical adherence to topical corticosteroids or corticosteroid combinations in patients with psoriasis and identifies 11 studies with varying observation periods and rates of non-adherence ranging from 8% to 88.3%. 34 multifactorial determinants of non-adherence were found, and one study tested an intervention that improved adherence. The studies were heterogeneous in design and had a high risk of bias, highlighting the need for further research on validated measurements of medical non-adherence, prescription registers, or medication weight to improve health outcomes in topical treatment of psoriasis. This article was authored by Mathias Tiedemann-Svenson, Fleming-Anderson, Jacob Hansen, and others.