 The Prisma statement is a reporting guideline for systematic reviews, SRs, and meta-analyses. Seven extensions have been published to address different types or aspects of SRs, and eight more are in development. A scoping review was conducted to map the research on the uptake and impact of the Prisma statement and extensions. The results suggest that reporting of many items in the Prisma statement is suboptimal, even in SRs published after 2009 when the guideline was disseminated. An update of the Prisma statement along with the toolkit may improve the transparency of SRs. This article was authored by Matthew J. Page and David Mower.