 Traditionally, biobutanol is produced with the AB, acetone butanol ethanol, process using clostridium species to ferment sugars from biomass. However, the root is associated with some disadvantages such as low butanol yield and by-product formation, acetone and ethanol. On the other hand, butanol can be directly produced from ethanol through aldol condensation over metal oxides slash hydroxyapatite catalysts. This paper suggests that the chemical conversion root is more preferable than the ABE process, because the reaction proceeds more quickly compared to the fermentation root and fewer steps are required to get to the product. This article was authored by Bin Daba, Aichi Enzu, and S Marks.