 Solibonin is a natural flavonoid compound that has been shown to be effective against certain types of cancer. In this study, researchers examined the effects of solibonin on inducing immunogenic cell death, ICD, in cancer cells. They found that solibonin alone could induce ICD in cancer cells, but when combined with chemotherapy drugs such as doxorubicin or oxalipitin, the effect was even more pronounced. This suggests that solibonin may enhance the anti-cancer effects of chemotherapy drugs. Additionally, solibonin was found to increase the production of damps, which are molecules released during cellular stress and inflammation. These damps include chalriticulin, high-mobility group box protein 1, and interleukin-12, all of which are associated with the body's immune system. Together, these results suggest that solibonin may help to activate the immune system and fight cancer. This article was authored by Sevda Jafari, Saba Hadarian, Raymond Lai, and others. We are article.tv, links in the description below.