 The study presents a comprehensive analysis of tandem repeats, TRs, based on high coverage whole genome sequencing from diverse individuals, revealing novel sequence features, population-specific tri-nucleotide expansions, and EQTL signals. Additionally, the study develops a method called EnsemblTR to integrate genotypes from four separate methods resulting in high-quality genotypes at over 1.7 million TR locky. The study also generates a phased-hapotype panel that can be used to impute most TRs with high accuracy, providing valuable resources for future studies of TRs and their role in human phenotypes.