 Multiple chronic diseases are becoming more common around the world, leading to increased morbidity and mortality rates. To address this issue, it is important to develop strategies that combine nutrition and physical activity components. Unfortunately, most research programs only focus on a single disease or condition instead of addressing the underlying causes of multiple chronic diseases. Exercise prescriptions should be tailored to each person's needs, including varying levels of intensity and types of exercises. Additionally, nutritional recommendations should be personalized for each patient, taking into account their specific medical history and current health status. These measures will help to reduce the prevalence of multiple chronic diseases and improve overall health outcomes. This article was authored by Ahmad Al-Khattib.