 The world is facing extremely complex issues today, and there are some that could kill millions of people and pose a great risk to humankind, disease outbreaks and the rise of terrorism. Unfortunately, the probabilities of global pandemics are increasing and many countries are dangerously underprepared. Disease outbreaks, which are also known as biological incidents, can occur anytime and anywhere. They can be of natural, accidental or deliberate origins. The outbreak of SARS in China and Canada in 2003, the Ebola outbreaks in West Africa in 2014 and 2016, as well as the MERS-related coronavirus that took place in 2012 in Saudi Arabia, are all examples of natural biological incidents. Some of the biological agents involved in natural outbreaks could potentially be used to cause harm to human populations. Law enforcement are increasingly focused on the prevention of terrorist acts, including intentional biological incidents as the damage caused by a biological attack could cause widespread illness and death and instill fear on a global scale. The term bioterrorism refers to the intentional release of biological agents or toxins for the purpose of harming or killing humans, animals or plants, with the intent to intimidate or coerce a government or civilian population to further political or social objectives. Intentional biological incidents call for law enforcement and public health to work together. But, regardless of the nature of the attack and methodology, these two sectors will need to deal with issues ranging from the quarantine of communities, controlling movement within and across borders, undertaking crime scene investigation, burial procedures, and collecting epidemiological information in order to understand the origin of the disease and control its progression. A strong working relationship between law enforcement and public health agencies involves training of frontline responders and health teams, and a return to basic instructions such as isolating and treating the sick, engaging and mobilizing affected communities as well as avoiding close contact, and using basic hygiene practices to prevent transmission. The bioterrorism represents a huge challenge for the community of the law enforcement services. For example, when we take the Ebola crisis, it is necessary that the security services work with the MECS. We cannot go to a random place to fight against an epidemic. The Ebola crisis was intersectorial, and the only sector of health could not apply all the dimensions of this fight. So, a certain number of ministers, including the security services and the application of the law, were asked to help us against this epidemic, which was a primary in our country. So, their role was to secure our interventions. They had the right to look at the transmission of diseases from one another, and also to limit the contact movement at risk in the localities we put in quarantine. We live today in a planetary village where we have to collaborate with others to acquire the least necessary means to secure their territory, their population and their well-being, but also to have the least necessary means for the human resource, so the training, the equipment and everything that goes with it, but also on the financial plan and the important institutions, such as Interpol, to put in place prevention and response devices in case it happens. Whether it is the Ebola epidemic or any other biological threat. The Interpol Bioterrorist Prevention Unit has developed a series of exercises and training that aim to evaluate national capacities to face biological incidents and support the development of coordinated, pluralistic strategies against these threats.