 Real-world data, RWD, and real-world evidence, RWE, are increasingly being used in healthcare decision-making, due to advances in technology and data collection methods. This paper reviews the current state of RWD-slash-e use in health technology assessments, HTAs, highlights key trends, and discusses potential opportunities for its use in Russia. This article was authored by E. A. Novotarevskina and S. Zaryanov.