 Polymer-based conductive electrodes, such as PEDIT-PSS, have become increasingly important in the development of flexible, transparent, and wearable electronic devices due to their unique properties. These electrodes can be used as transparent electrodes, whole transport layers, interconnectors, electroactive layers, or motion-sensing conductors. In this review paper, the authors discussed the current state of research on PEDIT-PSS, including its applications in flexible electronics, as well as the mechanisms behind its enhanced electrical conductivity and mechanical compliance and stability. They also highlight recent advances in devices with PEDIT-PSS, such as wearable, deformable, printable, and ultra-thin electronics. Finally, they provide insight into potential future directions for PEDIT, PSS, and other polymer-based conductive electrodes. This article is authored by Shefan, Wani Nya, Sinensai, and others.