 The AMBA study is a randomized, crossover, control trial designed to assess the effectiveness of virtual reality, VR-based serious games in improving vision, selective attention, and meta-control skills in individuals with residual ambliopia compared to refractive correction. The study will also compare the effects of VR-based serious games to a control group of age-matched healthy individuals. This article was authored by Christina Simon Matinas, Maria Paraskevi-Antonio, Wally Bautauer, and others.