 Biotechnology is a broad area of biology involving living systems and organisms to develop or make products. For any technological application that uses biological systems, living organisms, or derivatives near rough, to make or modify products or processes for specific use on convention on biological diversity, art, too. Depending on the tools and applications, it often overlaps with the related fields of molecular biology, bioengineering, biomedical engineering, biomanufacturing, molecular engineering, etc. For thousands of years, humankind has used biotechnology in agriculture, food production, and medicine. The term is largely believed to have been coined in 1919 by Hungarian engineer Kareli Harevki. In the late 20th and early 21st centuries, biotechnology has expanded to include new and diverse sciences such as genomics, recombinant gene techniques, applied immunology, and development of pharmaceutical therapies and diagnostic tests. The wide concept of biotech or biotechnology encompasses a wide range of procedures for modifying living organisms according to human purposes, going back to domestication of animals, cultivation of the plants, and improvements to these through-breeding programs that employ artificial selection and hybridization. Human usage also includes genetic engineering as well as cell and tissue culture technologies. The American Chemical Society defines biotechnology as the application of biological organisms, systems, or processes by various industries to learning about the science of life and the improvement of the value of materials and organisms such as pharmaceuticals, crops, and livestock.3 per the European Federation of Biotechnology, Biotechnology is the integration of natural science and organisms, cells, parts and rough, and molecular analogues for products and services.For biotechnology is based on the basic biological sciences e.g. molecular biology, biochemistry, cell biology, embryology, genetics, microbiology and conversely provides methods to support and perform basic research in biology.