 in Manipal Hospital, Bangalore. Atrial fibrillation being very common, there is lots of people who need anti-corbillation or some sort of therapy to prevent the stroke formation. It is believed that more than 90% of the plot in so called non-valuer atrial fibrillation actually occurs in one particular area which is called left atrial appendage. So if you can safely seal it off this area, then you don't need to take strong blood thinners. Here when we talk about blood thinners, we are not talking about aspirin or lumbaril. We are talking about something which is called anti-corbulance, which are much more important or much more stronger. So we are talking about Warfarin and we are talking about newer drugs. So when people take this drug, there is tendency to bleed. So as an alternative, this procedure is done. Now for the patients whom we do this procedure, it can be done in people with atrial fibrillation who have taken these drugs and who have already bled. There are lots of people who take Warfarin and other drugs and they do develop bleeding tendencies in whom this procedure can be done. It can also be done in people who are likely to bleed. So imagine there is somebody who has a liver problem, who is likely to bleed or who has had history of bleeding ulcer or who has had brain hemorrhage or bleeding anywhere. So these are the patients who are likely to bleed in whom we can do. It can also be done in people who have renal failure where taking drugs like Warfarin when they are on dialysis becomes very very difficult. So this is a good candidate for them. It can be done for people who have a recurrent stroke on anti-corbulation. It can also be done in people who have undergone angioplasty, now require two anti-corbulated labs and adding a third anti-corbulant would produce lots of bleeding. It can also be done as an alternative to anti-corbulation. So there are lots of indications for this procedure. What you should remember is this is not a treatment for atrial fibrillation itself. It is a treatment to prevent clot in atrial fibrillation. Hence it is an alternative to anti-corbulation. So that means patient with atrial fibrillation will continue to be in atrial fibrillation but that can be their heart rate can be controlled with drugs but a strong blood thinner can be avoided if they undergo a left atrial appendage closure.