 This study assesses the features, functionality, data security, and congruence with evidence of self-guided CBT-based apps targeting users affected by depression available in major app stores. The results show that only a few apps offer comprehensive CBT programs or suicide risk management resources, and sharing of user data is widespread. To fulfill their potential, self-guided CBT-based apps should follow evidence-based clinical guidelines, be patient-centered, and enhance users' data security. This article was authored by Laura Martinango, and Claire Stona, Constadena Griva, and others.