 This case report describes a child who had an unbalanced translocation resulting in a combination of partial trisomy 9p and partial monosomy 7p. This is believed to be the first time this combination has been reported. The presence of these two chromosome abnormalities was detected using conventional karyotyping and copy number variation sequencing, CNVSEC. This article was authored by Rui Li, Chao Jia Wang, Zhenhua Zhong, and others.