 This study investigated the expression levels of three DNA methyl transferase genes, DNMT1, DNMT3A and DNMT3B in patients with multiple myeloma and compared them to the global DNA methylation status of the same patients. The authors found no significant correlation between the expression levels of these genes and the clinical stage of the patients. However, they did find increased expression of the DNMT3A gene in both sorted and cell populations of patients with multiple myeloma. Additionally, the authors observed comparable results in the expression of DNA methyltransferases in both sorted and unsorted cell populations, suggesting that sorting may be a useful tool for reducing the number of analyses required. This article was authored by Petrelosna, Denisa Weiser-Joskova, Pavla Flodrova and others.