 Abstract cognitive impairment is one of the most common symptoms of post COVID-19 syndrome, also known as long COVID. Neuroimaging techniques, such as arterial spin labeling, ASL, MI can help us understand the pathophysiology behind this condition and its underlying mechanisms. In this study, we examined the brain perfusion alterations in post COVID-19 patients who reported subjective cognitive impairments after a mild SARS-CoV-2 infection. Our results suggest that these patients have a widespread hyper perfusion in their brains, particularly in the frontal, parietal and temporal lobes. This suggests that there is a large network dysfunction in post COVID-19 patients with cognitive complaints. Furthermore, the non-invasive nature of ASL MI makes it ideal for monitoring and prognosing post COVID-19 patients. This article was authored by Milo Shajevi, Katarina Iskra, Giovanni Ferlanese, and others. We are article.tv, links in the description below.