 This study investigated the effects of Abyssinia marina leaf extract on carbon tetrachloride-induced renal toxicity in rats. The results showed that the extract significantly decreased the levels of liver enzymes such as AST, ALT, and ALP, as well as lactic acid dehydrogenase, indicating that it may be effective in treating renal toxicity caused by carbon tetrachloride. Additionally, the extract was found to reduce necrosis, inflammation, and improve renal tubule structure. This suggests that Abyssinia marina leaf extract could be a potential therapeutic agent for treating renal toxicity caused by carbon tetrachloride. This article was authored by Nazar Maratzee, Sidenahid Movisag, and Mahmud Rafienko P.I.