 DFCP-1 is an essential component of autophagy, specifically for selective autophagy. It is responsible for the constriction of large omega-shaped structures containing autophagosomes, allowing them to be released into the cytoplasm for selective autophagy. Without DFCP-1, autophagy is impaired, resulting in decreased selective autophagy and increased accumulation of damaged organelles and protein aggregates. This article was authored by Viola Nas, Camilla Ryborg, Kia Wee Tan, and others.