 The obesity epidemic is caused by an imbalance between calories consumed and calories expended, as well as genetics and environmental factors. Recently, it has been found that exposure to endocrine-disrupting chemicals, EDCs, like tributyltin, TBT, during pregnancy and lactation, can lead to obesity in offspring. This is because EDCs can alter the expression of long non-coating RNAs, LNCRNAs, in gonadal white adipose tissue, which then affects the expression of genes involved in lipid and glucose metabolism, as well as insulin signaling. These changes in gene expression could potentially explain why EDCs cause obesity. This article was authored by Maria Fernanda de Silva Lopez, Juliana de Souza-Felix, Natalia Francisco Scaramille, and others.