 3D printing of multi-material composite structures using peak and CFR peak materials was studied to investigate the effects of building orientation on compression strength, failure mode, interface bonding quality, and strain fields. The results showed that the upright specimen had the highest compressive strength, while the flat specimen had the lowest due to poor fusion at the bottom interface. Applying interlayer inset and inlayer inset methods improved the compressive strengths of the upright specimen by 16.4% and 37.4%, respectively. This article was authored by Hufeng Jiang, particularly Ahimeti, Wurukai Shiayiti, and others.