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Published on Feb 20, 2018
Preview for the upcoming video on 2CN-NBOH synthesis, which is used in assays for novel anti-depressants and anti-psychotics. 25CN-NBOH is a potent agonist of the 5HT-2 receptor, but is remarkable in it's selectivity for the 2A subtype over 2C.
This is realtime footage of the recrystallization of phthalimido-2C-CN in absolute ethanol, the 3rd intermediate in this 5-step synthesis.
This compound has a really steep solubility curve in ethanol. After 8 minutes almost everything is crystallized while the solution is still warm, and recovery is often 95+%
I will release a video of each step as soon as it's done. I do suck at editing so you have to be patient, and a lot of footage is pretty bad because I have to film with one hand while doing chemistry with the other. For this reason not everything will be filmed.
SME (on behalf of Sony Music Entertainment); Abramus Digital, UMPI, SODRAC, EMI Music Publishing, UMPG Publishing, UBEM, AMRA, CMRRA, SOLAR Music Rights Management, União Brasileira de Compositores, and 9 Music Rights Societies
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