 Myrna-93 is a member of the Mir-106B-25 family and is encoded by a gene on chromosome 7Q22.1. It plays a role in the etiology of various diseases, including cancer, Parkinson's disease, hepatic injury, osteoarthritis, acute myocardial infarction, atherosclerosis, rheumatoid arthritis, and chronic kidney disease. Studies have shown that this Myrna has opposing roles in the context of cancer. Recent research suggests that Myrna-93 is down-regulated in breast cancer, gastric cancer, colorectal cancer, pancreatic cancer, bladder cancer, cervical cancer, and renal cancer. However, Myrna-93 is up-regulated in a wide variety of malignancies, such as lung, colorectal, glioma, prostate, osteosacoma, and hepatocellular carcinoma. The aim of the current review is to provide an overview of Myrna-93's function in cancer. This article was authored by Bashdam Ahmed Hussain, Snerusul Abdullah, Mohamed Fotirazal, and others.