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GI Effects GI Function Profile - Stool - Genova Diagnostics

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Published on May 1, 2009

CEO and founder, Dr. J. Alexander Bralley, discusses stool analysis and the development of the GI Effects test at Metametrix.

Advantages of the GI Effects Stool Profile
• Greater Accuracy
Microbial DNA analysis improves the accuracy of results and includes both aerobes and anaerobes. Anaerobes comprise over 95 percent of the bacteria in the gut.
• Maintaining Microbial Balance
Using DNA analysis, the specimen is placed in a fixative tube that stops microbial growth and offers a highly accurate snapshot of the microbial balance in the gut.
• Single Sample Collection
The GI Effects Stool Test requires only one sample collection leading to improved patient compliance.
• Antibiotic Resistant Genes
DNA analysis detects organisms possessing genes that give rise to antibiotic resistance, offering clinicians a superior tool for effective patient management.
• Increased Sensitivity
The GI Effects Stool Analyisis Test detects as few as 5 cells per gram.

Why Use Stool Analysis?
Gastrointestinal function is important for general health. The intestinal tract contains significant amounts of bacteria - some beneficial, some neutral, and some harmful. Balancing beneficial microbial flora in the gut is key in digestion, nutrient usage, and ridding the body of waste and pathogens. Poor digestion and malabsorption can lead to immune dysfunction, nutritional insufficiencies, mental/emotional disorders, and autoimmune diseases.

• Anaerobes
Anaerobes, making up over 95 percent of microbiota in the gut, can be identified and quantified using GI Effects.
• Parasites
Detects parasites in the smallest concentration per specimen - 5 cells per gram.
• Adiposity Index
Measure imbalances of the two predominant bacterial groups in the human GI tract, bacteroidetes and firmicutes, which can lead to obesity.
• Drug Resistance Genes
Identifies drug resistance genes to help with patient treatment and health maintenance.
• Absorption
Indicates absorption issues with elevated levels of long-chain fatty acids, cholesterol, or total fat (the sum of gut lipids).
• Inflammation
Lactoferrin is a marker of acute inflammation. It helps differentiate IBD from IBS.
• Sensitivities
Pharmaceutical and botanical sensitivities widen treatment options.

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